Health Organisation, Malaria Comission; World Health Organization : Organisation Mondiale de la Sante; Serie de Monographies, Issue No. 72. 779: Factors Influencing the Course of Blood-Induced Rodent Malaria and the Effect of Drug Treatment in the Laboratory Mouse

By W. Kretschmar

Book Id: WPLBN0000082879
Format Type: PDF eBook
File Size: 2.8 MB
Reproduction Date: 2005

Title:	Health Organisation, Malaria Comission; World Health Organization : Organisation Mondiale de la Sante; Serie de Monographies, Issue No. 72. 779: Factors Influencing the Course of Blood-Induced Rodent Malaria and the Effect of Drug Treatment in the Laboratory Mouse
Author:	W. Kretschmar
Volume:
Language:	English
Subject:	Health., Public health, Wellness programs
Collections:	Medical Library Collection, World Health Collection
Historic Publication Date:
Publisher:	World Health Organization


Citation APA MLA Chicago Kretschmar, W. (n.d.). Health Organisation, Malaria Comission; World Health Organization : Organisation Mondiale de la Sante; Serie de Monographies, Issue No. 72. 779. Retrieved from http://gutenberg.cc/

Description
Medical Reference Publication

Excerpt
The issue of this document does not constitute formal publication. It should not be reviewed, abstracted or quoted without the agreement of the World Health Organization. Authors alone are responsible for views expressed in signed articles. Ce document ne constitue pas une publication. I I ne doit faire I'objet d'aucun compte rendu ou resume ni d'aucune citation sans I'autorisation de 190rganisation Mondiale de la Sante. Les opinions exprimkes dans les articles sign& n'engagent que leurs auteurs.

Table of Contents
CONTENTS Page 1. Parasite-host r e l a t i o n s h i p . . . . . . . . . . . , . . . . . . . . . . . . . . . . . . 4 1.1 Species and s t r a i n s of rodent plasmodia . . . . . . . . . . . . . . . . . . . 4 1.2 Mousestrains . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 1.2.1 The NMRI mouse . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 1.2.2 Genetics of mouse s t r a i n s and course of i n f e c t i o n . . . . . . . . . . 4 1.2.3 Susceptibility of mouse s t r a i n s and levels of parasitaemia . . . . . . 5 1.3 Correlation of parasitaemia t o polychromasia . . . . . . . . . . . . . . . . . 5 1.3.1 Predilection of plasmodia for mature and immature erythrocytes . . . . 5 1.3.2 Parasite multiplication depending on invasion of mature or immature erythrocytes . . . . . . . . . . . . . . . . . . . . . . . 5 1.3.3 Mortality depending on invasion of mature or immature erythrocytes . . 5 1.4 Acquired protective immunity . . . . . . . . . . . . . . . . . . . . . . . . . . 6 1.4.1 Characteristics of immunity . . . . . . . . . . . . . . . . . . . . . 6 1.4.2 Acquisitionofimmunity . . . . . . . . . . . . . . . . . . . . . . . 6 2. Factors influencing the course of infection . . . . . . . . . . . . . . . . . . . . 6 2.1 Infectiveinoculum . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 2.1.1 Time required for preparation of inoculum . . . . . . . . . . . . . . 6 2.1.2 Temperatureofprocessingtheinoculum. . . . . . . . . . . . . . . . . 7 2.1.3 Route of inoculation . . . . . . . . . . . . . . . . . . . . . . . . . 7 2.2 Concomitant i n f e c t i o n s . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7