World Health Organization : Year 1993 ; World Health Organization, Hereditary Disease Program Tif Ha, No. 93.1: Joint World Health Organization/TIF Meeting on the Prevention and Control of Haemoglobinopathies (7th Meeting of the World Health Organization Working Group on the Control of Hereditaq Anaemias)

By S. Al-Arrayed

Book Id: WPLBN0000103314
Format Type: PDF eBook:
File Size: 1.0 MB
Reproduction Date: 2005

Title:	World Health Organization : Year 1993 ; World Health Organization, Hereditary Disease Program Tif Ha, No. 93.1: Joint World Health Organization/TIF Meeting on the Prevention and Control of Haemoglobinopathies (7th Meeting of the World Health Organization Working Group on the Control of Hereditaq Anaemias)
Author:	S. Al-Arrayed
Volume:
Language:	English
Subject:	Health., Public health, Wellness programs
Collections:	Medical Library Collection, World Health Collection
Historic Publication Date:
Publisher:	World Health Organization


Citation APA MLA Chicago Al Arrayed, B. S. (n.d.). World Health Organization : Year 1993 ; World Health Organization, Hereditary Disease Program Tif Ha, No. 93.1. Retrieved from http://gutenberg.cc/

Description
Medical Reference Publication

Excerpt
INTRODUCTION Haemoglobinopathies - thalassaemias and sickle cell disorder (SCD) - are widespread recessive inherited diseases. A t present, about 250.million people (4.5% of the world population) carry a potentially pathological haemoglobinopathy gene. Each year about 300,000 infants are born with major haemoglobinopathies. The hereditary anaemias were originally confined to the lu sub-tropics and tropics, their high incidence being due to the fact that healthy carriers are protected against lethal effects of malaria. However, increasing global migration has introduced the haemoglobinopathies into many areas where they were not originally endemic. In the USA, 10% of the population is at risk for SCD, and in North-West Europe, between 2% and 9% of most populations now belong to ethnic minorities at risk for the haemoglobinopathles. In some Souch- East Asian countries, population movement could increase the potential birthrate of infants with thalassaemia. Globally, there are more carriers of thalassaemia than of SCD, but the high frequency of the sickle cell gene in certain areas leads to a high birth rate of homozygotes. As a result, SCD accounts for about 70% of haemoglobin disorders worldwide. Nearly 70% of affected births occur in sub-Saharan Africa where up to 2% of all children are born with SCD. This high frequency makes the African Region a global focus of haemoglobin disorder^'^^^^.

Table of Contents
List of Contr?ts DISTR. : LlMlTEU DISTR. : LIMITEE WHO/WDP/TIF/HA/~~.~ ENGLISH ONLY INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 PROGRESS IN ONGOING PROGRAMMES FOR THE CONTRaL OF HAEMOGLOBIN DlSORDERS . 2 2.1 Africa . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2.2 The Americas . 2.3 The Eastern Med. it.er.ra.ne.an. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. 35 2.4 Europe . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 2.5 South-EastAsia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 2.6 The Western Pacific . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 CONCLUSIONS AND RECOMMENDATIONS . . . . . . . . . . . . . . . . . . . . . . 13 LISTOFPARTICIPANTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 ACKNOWLEDGEMENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 REFERENCES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 FIGURES (3) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 TABLES(8) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 ANNEX 1: Educational materials on haemoglobin disorders . . . . . . . . . . . 29 ANNEX 2: Contents of WHO guidelines for the control of haemoglobin disorders . . . . . . . . . . . . ANNEX 3: List of working papers available upon request . . . . . . . . . . . . 31