World Health Organization : Year 1988 ; The Special Programme for Research and Training in Tropical Diseases Try Sc-Swg (1) Issue 88.3: Report of the Meeting of the Joint Steering Committees of the Scientific Working Group on African Trypanosomaises

By World Health Organization

Book Id: WPLBN0000198052
Format Type: PDF eBook
File Size: 0.5 MB
Reproduction Date: 2005

Title:	World Health Organization : Year 1988 ; The Special Programme for Research and Training in Tropical Diseases Try Sc-Swg (1) Issue 88.3: Report of the Meeting of the Joint Steering Committees of the Scientific Working Group on African Trypanosomaises
Author:	World Health Organization
Volume:
Language:	English
Subject:	Health., Public health, Wellness programs
Collections:	Medical Library Collection, World Health Collection
Historic Publication Date:
Publisher:	World Health Organization


Citation APA MLA Chicago Organization, W. H. (n.d.). World Health Organization : Year 1988 ; The Special Programme for Research and Training in Tropical Diseases Try Sc-Swg (1) Issue 88.3. Retrieved from http://gutenberg.cc/

Description
Medical Reference Publication

Excerpt
1. INTRODUCTION African trypanosorniasfs shows a range of clinical manifestations it] diverse ecological and epidemiological situations, requiring different approaches to conrrol.. Scienrific progress during the past ten years, assisted hy funding from the UNDP/WORLD BANK/WHO Special Programme for Research and Training in Tropical Diseases (TDR), has advanced our understanding of thc disease and prompted the development of new tools for control.

Table of Contents
CONTENTS 743 i 1. INTRODUCTION ....... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 I 2. EPIDEMIOLOGY AND VECTOR BIOLOGY A*TD CONTROL 2 2.1 Field Research . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2 . 1 . 1 Protocols . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2.1.2 Epidemiological Analysis of Fiald Research . . . . . . . . . . . . 2 2.1.3 Socio-economic aspects ................................ 3 2.1.4 Multidisciplinary approach 3 2.2 Laboratory Research .......................................... 4 2 . 2 . 2 Vector and host-vector relationship . . . . . . . . . . . . . . . . . . . 4 2 . 2 . 2 Parasite .............................................. l 4 3 . CHEMOTHERAPY AND DRUG DEVEMPMENT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 3.1 Approaches in the Saarch of New Compounds . . . . . . . . . . . . . . . . . . . . 5 3.2 Screening Activities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 3.2.1 Animal models . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 3 . 2 . 2 In vi'cr~ screening . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 3.6 Drug Resistance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 4. IMMUNOLOGY AND PATHOLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 4.1 Immune Response . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 4 . 2 Clinical signs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 4 . 3 Experimental Pathology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 4 . 4 Models for Clinical and Pathological Evaluation of Treatment ................................................. 9 5 . PROSPECTS FOR THE APPLICATION OF NEW TOOLS IN DISEASE CONTROL . . . . . 9 6. PARTICIPANTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 ANNEX : REPORT ON THE WORKSHOP ON MODELLING SLEEPING SICKNESS EPIDEMIOLOGY AND CONTROL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12